San Cosme y Damian Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top San Cosme y Damian Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Luxuri Suites
South Beach
CA $754
per person
Sep 23 - Sep 30
found 18 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to Miami (MIA)
6.8/10 (57 reviews)
Ok the fact we had no desk for check was terrible. I could not check in due to a code for door and room acess never being sent to my email resulted in me not checking for 3hours until I was told about a sister property 3 blocks from where I was stay had to walk in the rain to the siater property for thwm to grant me acess codes to get into my room now at 3am. I wouls likw to be reemburst for that night and day. My TV had no working batteries and once I go batteries the TV volum did not work.
Reviewed on Jul 9, 2026
The Retreat Collection at 1 Hotel & Homes South Beach
South Beach
CA $15,948
per person
Oct 1 - Oct 6
found 1 hour ago
Roundtrip non-stop flight included
Calgary (YYC) to Miami (MIA)
8/10 Very good! (1 review)
Horrible checkin / checkout... Would never stay there again...Double charged me entire stay and still fighting to get someone to refund 2nd one that is so clearly a duplicate for same stay....
Reviewed on Jun 22, 2016
One Bedroom | 1.5 Baths & Living Room | Jet Tub – Palms Place StripSuite- NO RESORT FEE
CA $3,359
per person
Sep 19 - Sep 26
found 20 hours ago
Roundtrip non-stop flight included
Vancouver (YVR) to Las Vegas (LAS)
8.6/10 Excellent! (4 reviews)
The view was gorgeous at night with all the lights. We loved it! ~ Always Grateful. ~
Reviewed on May 7, 2026
Ready to book your vacation to San Cosme y Damian?
San Cosme y Damian Hotel Deals
Sun Hotel
Encarnacion Itapúa
CA $81
CA $89 total
Aug 17 - Aug 18
includes taxes & fees
9/10 Wonderful! (135 reviews)
"Muy bien ubicado"
Reviewed on Aug 9, 2026
Carnaval Hotel Casino
Av. Irrazabal, 750 Encarnacion
CA $94
CA $103 total
Sep 6 - Sep 7
includes taxes & fees
9.4/10 Exceptional! (204 reviews)
"Muuuuy recomendado. Buenos amenities y buenisisima ubicación. Desayuno completisimo."
Reviewed on Jul 19, 2026
Alula Hotel Encarnacion
1848 Gral Aquino Encarnación Itapúa
CA $123
CA $136 total
Sep 16 - Sep 17
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular San Cosme y Damian attractions
Guarani Jesuit Ruins of San Cosme and San Damián
Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area.
Buenaventura Suarez Planetarium
9.0/10 (2 reviews)
You can spend time browsing the exhibits at Buenaventura Suarez Planetarium during your travels in San Cosme y Damian. Take in the museums while you're in the area.
Frequently asked questions
How much does a San Cosme y Damian vacation package cost?
You can grab a vacation package to this popular destination from CA $599 on Expedia. However, how much your vacation to San Cosme y Damian costs will depend on your hotel choice, length of stay and season.
What are the cheapest months to go to San Cosme y Damian?
January, February and April are great times to look for cheap San Cosme y Damian vacation packages. Opting to travel in less busy months means you can typically find reduced prices on flights and hotels.
How many days is enough for San Cosme y Damian?
With a well-organized travel plan, you can easily tick off the most popular San Cosme y Damian attractions in a few days. But if you want to venture off the beaten track or go on day trips, consider booking your San Cosme y Damian vacation for longer.
How to find the best San Cosme y Damian package deals?
Use Expedia's filters to help you find some tempting San Cosme y Damian package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your adventure for midweek, or browse for San Cosme y Damian package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package well in advance.
Is it cheaper to book a San Cosme y Damian vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, car rental and hotel into one great-value price and enjoy significant savings. You'll typically score a better deal than booking each component individually. And you'll still have the freedom to create a customized San Cosme y Damian vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to San Cosme y Damian?
Score incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for an impromptu San Cosme y Damian trip.
How to plan a trip to San Cosme y Damian?
- Pick your dates: The things you want to do in San Cosme y Damian and your preferred season can help you decide when to go.
- Set your budget: Consider expenses like transportation, flights and meals when calculating how much to save for your trip to San Cosme y Damian. Then, choose a property that works with your budget, whether that's an affordable option or a deluxe getaway.
- Set the duration of your trip: Start by listing all the sights and activities you'd like to get to in San Cosme y Damian. Then, estimate how long you'll need at each, including any travel time.
- Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to choose a San Cosme y Damian vacation package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
